One complication of diabetes is slow healing process in the wounds so a research group led by Doctor Juan Manuel Bellon and Doctor Julia Bujan worked to develop a model that releases growth hormone directly over the wound. They did this in a controlled and gradual way. What did they find? They found the healing process improves.
This type of therapy was successfully tested with the use of diabetic lab rats. They published their findings in the Journal of Biomedical Materials. They found that applying the growth hormone directly over the wound helps in the regeneration of tissues and skin.
They said that after an average of 15 days, the healing of a sample wound in normal rats is complete. When this was done to diabetic rats, the healing was complete after 30 days. The team that investigated this is composed of histologists, surgeons, chemists, biologists and pharmacists from the Surgery Department. The groups dedicated itself for more than twenty years in investigating tissue repair.
Scientists found that protein could help restore the tissues that are starved of oxygen. This way the wounds are healed. They tried to find this so they could lay out a strategy to treat the tissues like those damaged by diabetes. They tried to generate the production of blood vessels that are healthy but found the capillaries leaky.
Then the researchers tried it again with mice that are genetically engineered. This time the capillaries in the skin of the mice increased to almost 7o%. There was no swelling or inflammation and more significantly there was no leakage.
I don’t know where they are going with this and I tried to follow them up but I didn’t find any. I was surprised because they were so excited with the result of their research and of course I was awaiting what they will do for the diabetics who have problem with wounds and their diabetic foot ulcer.
No comments:
Post a Comment